Abstract:
With the improvement of people's living standards and the change of lifestyle, cancer has become a main factor affecting people’s lifespan. Currently, clinicians make a preliminary diagnosis of cancer based on clinical symptoms, imaging findings, and blood tumor markers, and the definite diagnosis is mainly based on findings of pathological examinations of tumor tissues. Tissue biopsy is invasive, and blood-based liquid biopsy components such as circulating tumor DNA (ctDNA), circulating tumor cells(CTC), extracellular vesicles(EVs), and tumor-educated platelets (TEPs) are widely used for diagnosing cancer. Many studies have shown that TEPs play an important role in the early diagnosis, treatment, progression, and metastasis of tumors and have great potential for clinical application. This study reviews the progress of TEPs in the noninvasive diagnosis of various tumors.
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