Objective   To analyze the risk factors of poor incision healing after laparoscopic-assisted radical gastrectomy.

  Methods   Two hundred and ninety-six patients who underwent laparoscopic-assisted radical gastrectomy at The Second Affiliated Hospital of Zhengzhou University from March 2017 to July 2020 were analyzed retrospectively. The relationship between the occurrence of poor incision healing and sex, age, body mass index (BMI), diabetes, hypertension, preoperative levels of hemoglobin and serum albumin, preoperative use of anticoagulant, neoadjuvant chemotherapy, operation time, intraoperative blood loss, tumor size, and postoperative hyperthermic intraperitoneal chemotherapy were statistically analyzed. Further multivariate Logistic regression analysis was performed to analyze the independent risk factors for poor incision healing.

  Results  Seventeen (5.7%) of the 296 patients showed poor incision healing, including 11 cases of incision infection and 6 cases of fat liquefaction. The results of univariate analysis indicated that there were statistically significant differences between the good incision healing group and the poor incision healing group in terms of age, BMI, history of diabetes, hemoglobin level, and serum albumin level (P<0.05). Furthermore, the results of multivariate Logistic regression analysis showed that age > 65 years (OR=3.434, 95%CI: 1.035-11.394, P=0.044), BMI (OR=O.629, 95%CI: 1.365-2.579, P<0.001), and serum albumin≤35 g/L (OR=1.368, 95%CI: 1.166-13.232, P=0.027) were independent risk factors for poor incision healing after laparoscopic-assisted radical gastrectomy.

  Conclusions  Senility, obesity, and hypoproteinemia are independent risk factors for poor incision healing after laparoscopic-assisted radical gastrectomy. Patients with the above risk factors should guard against the occurrence of poor incision healing after surgery.