Abstract: Video-assisted thoracoscopic surgery (VATS) is the most used, minimally invasive surgical method in the treatment of lung cancer. Despite this, VATS still needs to be improved to better facilitate patient comfort and promote rapid recovery after surgery. A new tubeless VATS technique is being developed to avoid the practice of tracheal intubation and the use of central lines, epidural or chest tubes, and urinary catheters in patients requiring thoracoscopic surgery. The new tubeless VATS technique combines highly evolved and less invasive techniques used in anesthesia, video-assisted surgery, and perioperative care to ensure safe and feasible surgery, allowing patients to achieve early postoperative oral feeding, ambulation, and discharge. Tubeless VATS is thus excellent in enabling thoracic day surgery. The application of tubeless VATS in lung cancer and thoracic surgery has optimized minimally invasive thoracoscopic surgery technique. Additionally, tubeless VATS can maximize patient benefit from fast track surgery.