于旭耀, 王煜雯, 宋勇春. 立体定向放疗在超中央型肺癌治疗中的应用进展[J]. 中国肿瘤临床, 2023, 50(2): 104-108. DOI: 10.12354/j.issn.1000-8179.2023.20220930
引用本文: 于旭耀, 王煜雯, 宋勇春. 立体定向放疗在超中央型肺癌治疗中的应用进展[J]. 中国肿瘤临床, 2023, 50(2): 104-108. DOI: 10.12354/j.issn.1000-8179.2023.20220930
Xuyao Yu, Yuwen Wang, Yongchun Song. Advances in stereotactic body radiation therapy for ultra-central lung cancer[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2023, 50(2): 104-108. DOI: 10.12354/j.issn.1000-8179.2023.20220930
Citation: Xuyao Yu, Yuwen Wang, Yongchun Song. Advances in stereotactic body radiation therapy for ultra-central lung cancer[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2023, 50(2): 104-108. DOI: 10.12354/j.issn.1000-8179.2023.20220930

立体定向放疗在超中央型肺癌治疗中的应用进展

Advances in stereotactic body radiation therapy for ultra-central lung cancer

  • 摘要: 立体定向放射治疗(stereotactic body radiation therapy,SBRT)可实现不可手术超中央型肺癌(ultra-central lung cancer,UCLC)患者的靶区高剂量照射并较好保护危及器官,是目前临床治疗的探索热点。接受SBRT治疗后UCLC患者可获得较好的局部控制率、中位生存时间和总生存率,但是由于UCLC紧邻或侵犯纵隔内重要脏器,SBRT治疗会常伴有一定的不良反应风险。本文就SBRT应用于UCLC患者的临床实践及研究进展进行综述。

     

    Abstract: Stereotactic body radiation therapy (SBRT) can achieve high-dose irradiation in the target areas of patients with ultra-central lung cancer (UCLC) while also protecting the surrounding organs at risk. SBRT is the gold standard of clinical treatment for patients with UCLC. Some clinical studies on SBRT for UCLC treatment have shown that it can obtain a better local control rate, median survival time, and overall survival rate than other known treatment methods. However, because UCLC tissues are close to organs at risk in the patient's mediastinum, SBRT treatment is often accompanied by toxicity and side effects. This article reviews the progress of research on SBRT for the treatment of patients with UCLC.

     

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