刘春艳, 刘文欣. 免疫治疗在局部晚期宫颈癌中的研究进展[J]. 中国肿瘤临床, 2023, 50(24): 1280-1283. DOI: 10.12354/j.issn.1000-8179.2023.20231124
引用本文: 刘春艳, 刘文欣. 免疫治疗在局部晚期宫颈癌中的研究进展[J]. 中国肿瘤临床, 2023, 50(24): 1280-1283. DOI: 10.12354/j.issn.1000-8179.2023.20231124
Chunyan Liu, Wenxin Liu. Research progress of immunotherapy in locally advanced cervical cancer[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2023, 50(24): 1280-1283. DOI: 10.12354/j.issn.1000-8179.2023.20231124
Citation: Chunyan Liu, Wenxin Liu. Research progress of immunotherapy in locally advanced cervical cancer[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2023, 50(24): 1280-1283. DOI: 10.12354/j.issn.1000-8179.2023.20231124

免疫治疗在局部晚期宫颈癌中的研究进展

Research progress of immunotherapy in locally advanced cervical cancer

  • 摘要: 宫颈癌是女性最常见的生殖系统恶性肿瘤,高危型人乳头状瘤病毒持续感染是其主要致病因素。传统治疗方法包括手术、放疗和化疗,但对晚期宫颈癌患者的预后并不理想。近年来治疗性疫苗、免疫检查点抑制剂和过继性T细胞疗法等免疫治疗在宫颈癌中应用广泛,显著改善了患者的生存期。本文将对免疫治疗在局部晚期宫颈癌中的临床研究及相关进展进行综述。

     

    Abstract: Cervical cancer is the most common reproductive system malignancy in women. Its primary cause is persistent infection with high-risk human papillomavirus. Traditional treatment methods include surgery, radiotherapy, and chemotherapy, but the prognosis for advanced cervical cancer remains dismal. In recent years, therapeutic vaccines, immune checkpoint inhibitors, adoptive T cell therapy, and other immunotherapies have been widely used in cervical cancer, notably improving patient survival. This article reviews clinical trials and recent advances in immunotherapy for in locally advanced cervical cancer (LACC).

     

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