Abstract:
Objective: To evaluate the surgical procedures and prognostic factors for colorectal carcinoma in patients aged over 70. Methods:We retrospectively reviewed 31colorectal cancer patients aged over 70seen in our hospital be-tween January 1992 and December 2001. Treatment procedures and outcome of these patients were analyzed. Ka -plan-Meier method was used for survival analysis and Cox regression analysis was conducted to analyze prognostic fac-tors. Results: The median age of these patients was74years. The median follow-up period was 12months. The postopera-tive complication rate was 22.6% . The thirty-days mortality was 6.5% . There were 28cases of tubular adenocarcinoma (well differentiated in 5 cases, moderately differentiated in 16cases, and poorly differentiated in 7 cases) and 3 cases of mucinous adenocarcinoma. As to Dukes stage, there were8 cases of B stage, 9 cases of C stge, and 14cases of D stage. The overall5-year survival rate was 22.7%. The5-year survival rate was 44.4% in the radical surgery group and 7.7% in the palliative surgery group. The median survival period of all patients was 12months. The median survival period was38 months in the radical surgery group and 9 months in the palliative surgery group. Univariate analysis showed that the pre-dictors for survival were age, co-morbidity, preoperative serum CEA level, preoperative serum albumin concentration, dura-tion of surgery, radical surgery, and cancer stage. Conclusion:Radical resection is a prerequisite for cure of colorectal can-cer with obstruction in elderly patients. Age and preoperative serum albumin concentration are independent prognostic indi-cators.