Abstract:
Objective:To evaluate the advantages of stereotactic biopsy with vacuum-assisted biopsy device in early di -agnosis of Stage-T0 breast cancer patients. Methods: From October2007to September 2009, The Vacora vacuum-assisted biopsy device was conducted in243 cases with clinically non-palpable suspicious lesions (Stage-IV and above by BI-RADS rating) in our hospital. Stereotactic biopsy was performed with Lorad Multicare Prone Breast Biopsy System with digital imaging capabilities (StereoGuide with Digital Spot Mammography; LoRad, US). Results:The success rate of biopsy was 99.6% (242 / 243 ). The time of surgery ranged from20to 60minutes, with the median time of32. Post-operative pathological examination demonstrated that ductal carcinoma in situ occurred in 21of the cases, ductal carcinoma in situ with micro-invasion in 7 cases, infiltrating duct carcinoma in 2 cases, and invasive lobular carcinoma in 1 case. Based on the pathologic TNM staging, there were21cases with Stage-0, 9 cases with Stage-I, and 1 case with Stage-IIA. Atypical hyperplasia was found in 21cases, accounting for9.1% of the total undergoing the biopsy. Postoperative complications included subcutaneous ecchymosis in15 cases and hematoma in 11cases. No other severe complications were found. Conclusion:The MultiCare digital intervention system guided Vacura vacuum biopsy is valuable in assessing the impalpable breast lesions in early diagnosis of Stage-T0 breast cancer patients.