<sup>125</sup>I 粒子植入术治疗门静脉癌栓40例近期疗效观察

彭齐荣; 肖 必; 王 峥①; 程 涛; 罗鹏飞②

doi:10.3969/j.issn.1000-8179.2010.19.009

¹²⁵I 粒子植入术治疗门静脉癌栓40例近期疗效观察

doi: 10.3969/j.issn.1000-8179.2010.19.009

作者单位:中国人民解放军第458 医院全军肝病中心(广州市510602);①CT室;②广东省人民医院肿瘤中心介入科

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出版历程
- 收稿日期: 2009-12-28
- 录用日期: 2010-10-15
- 修回日期: 2010-02-11
- 刊出日期: 2010-10-15

Short-term Efficacy of 125I Seed Implantation Treatment for Portal Vein Tumor Thrombus

The Liver Disease Center of the PLA, The 458 th Hospital of the PLA, Guangzhou 510602, China

摘要

摘要: 目的：探讨CT导向下¹²⁵I 粒子植入治疗门静脉癌栓的临床价值和操作流程。方法：选取40例原发性肝细胞癌伴门静脉癌栓患者，采用TPS 计算布源，在CT导向下将¹²⁵I 粒子植入瘤灶内，采用（2.2～3.3）× 10⁷Mq活度的125I 粒子多层面播植。结果：40例患者中癌栓完全缓解18例（45.0%），部分缓解22例（55.0%），总有效率100% 。所有患者均未发生手术相关严重并发症。结论：CT导向下¹²⁵I 粒子植入治疗门静脉癌栓近期效果好，安全性高，创伤小，并发症发生率低。
- 碘放射性核素 /
- 门静脉癌栓 /
- ¹²⁵I 粒子植入术
Abstract: Objective: To investigate the clinical value of CT-guided ¹²⁵I radioactive seed implantation in treating portal vein tumor thrombus. Methods:A total of 40hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus were collected. Under CT guidance, ¹²⁵I seeds of 2.2 × 10⁷ to 3.3 × 10⁷ Mq were implanted into the metastatic lymph nodes accord-ing to TPS. Results: Of the 40 patients, 18 cases (45.0% ) achieved complete remission (CR), and22 cases (55.0% ) achieved partial remission (PR). The overall response rate was 100 % . No serious complications were observed.Conclusion: CT-guided ¹²⁵I radioactive seed implantation is effective and safe in treating portal vein tumor thrombus with minimal damage and few complications.
- Iodine radioisotopes /
- Portal vein /
- Iodine monochloride