Abstract: Objective:To compare the clinical features and survival for patients with triple negative breast cancer (TN -BC) between different age groups (<35years and ≥35years) and to analyze the prognosis of young patients with TNBC. Methods:The clinical data and survival status of 543 cases of operable TNBC treated in our hospital between January 2002and December 2004were collected. SPSS13.0 software was used for statistical analysis. Results:Compared with TN-BC in women of 35 or older, the younger patients showed special features. There were 7.96% patients who were below35 years old, of these 37.21% were of clinical stageⅢ(P=0.027 ), 39.53 % had tumor size larger than 5 cm (P=0.000 ), 37.21% were of histological grade Ⅲ(P=0.015 ), 62.79% had positive lymph node status (P=0.012 ), 53.49% received post-operative radiotherapy ( P=0.009 ), and 44.19% had recurrence or metastasis within 5 years (P=0.000 ). The 5-year dis-ease-free survival ( 53.49% ,P=0.000 ) and overall survival (67.44% ,P=0.000 ) were significantly different between the two groups with TNBC. For young patients with TNBC, univariate analysis and multivariate Cox regression analysis showed that tumor size, lymph node status and histological grade were independent prognostic factors. Conclusion:Triple negative breast cancer is generally characterized by large tumor size, high degree of malignancy, high rate of metastasis and recur-rence, late onset and poor prognosis. Studies to explore more effective treatment are warranted.