金哈斯, 宫丽平, 倪美兰, 孟文霞, 林美雄, 母立新. 腹膜后肿块为首发症状的恶性淋巴瘤临床特点分析[J]. 中国肿瘤临床, 2012, 39(6): 343-347. DOI: 10.3969/j.issn.1000-8179.2012.06.012
引用本文: 金哈斯, 宫丽平, 倪美兰, 孟文霞, 林美雄, 母立新. 腹膜后肿块为首发症状的恶性淋巴瘤临床特点分析[J]. 中国肿瘤临床, 2012, 39(6): 343-347. DOI: 10.3969/j.issn.1000-8179.2012.06.012
shu
Hasi JIN, Liping GONG, Meilan NI, Wenxia MEN, Meixiong LIN, Lixin MU. Clinical Characteristics of Malignant Lymphoma with Retroperitoneal Mass as the Primary Presentation[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2012, 39(6): 343-347. DOI: 10.3969/j.issn.1000-8179.2012.06.012
Citation: Hasi JIN, Liping GONG, Meilan NI, Wenxia MEN, Meixiong LIN, Lixin MU. Clinical Characteristics of Malignant Lymphoma with Retroperitoneal Mass as the Primary Presentation[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2012, 39(6): 343-347. DOI: 10.3969/j.issn.1000-8179.2012.06.012
shu

腹膜后肿块为首发症状的恶性淋巴瘤临床特点分析

Clinical Characteristics of Malignant Lymphoma with Retroperitoneal Mass as the Primary Presentation

    摘要
  • 摘要:
      目的  探讨腹膜后肿块为首发症状的恶性淋巴瘤的临床特点、治疗及预后。
      方法  回顾性收集自2002年1月至2010年12月间收治的20例腹膜后肿块为首发症状的恶性淋巴瘤患者的临床资料, 分析其病理活检方式、病理类型、免疫组化、分期、治疗效果、生存率等。研究手术、年龄、性别、分期、巨大包块、B症状、病理类型对近期疗效的影响。
      结果  20例患者中11例（55%）为弥漫大B细胞性淋巴瘤, 4例（20%）为滤泡性淋巴瘤, 2例（10%）为小淋巴细胞性淋巴瘤/慢性淋巴细胞白血病, 1例（5%）为淋巴母细胞性淋巴瘤, 1例（5%）为间变细胞淋巴瘤, 1例（5%）霍奇金淋巴瘤。全组患者化疗后完全缓解7例（35%）, 部分缓解8例（40%）; 5例就诊后3个月之内早期死亡, 9例起病后4~36个月之间疾病进展或复发死亡。全组患者中5年生存率仅20%。手术、病理类型、年龄、大包块、浸润周围器官广泛、静脉血栓形成、肝功能异常、B症状对近期疗效有明显影响。
      结论  腹膜后肿块为首发症状的恶性淋巴瘤缓解率和长期生存率较低, 预后差。病理类型、手术、大包块、浸润周围器官、肝功能异常、静脉血栓形成、B症状对缓解率和长期生存率有明显影响。

     

    Abstract:
      Objective  To investigate the clinical characteristics, treatment outcomes and prognostic factors of patients with malignant lymphoma with primary retroperitoneal mas as the primary presentation.
      Methods  A total 20 cases of malignant lymphoma with primary retroperitoneal presentation lymphoma seen in our hospital from January 2002 to Decemter 2010 Biopsy method, tissue pathology, immunochemistry, treatmemt outcome and long time survival were analyzed retrospectively. The influences of age, sex, pathologic type, clinical stage, huge mass and B symptom were analyzed.
      Results  Among the 20 cases, 11 (55 %) were diffuse large B cell lymphoma, 4 (20 %) were follicular lymphoma, 2 (10 %) were B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma, 1 (5%) was lymphoblastic lymphoma, 1 (5 %) was anaplastic large cell lymphoma and 1 (5 %) was Hodgkin lymphoma. Among the 20 cases, 7 (35 %) had complete remission, 8 (40 %) had partial remission, 5 (25 %) died. The 3-year accumulated survival of the whole group was 30 %, The 5-year accumulated survival of the whole group was only 20%.
      Conclusion  Complete remission rate and long term survival rates of malignant lymphoma with primary retroperitoneal presentation were low. Pathological type, surgery, huge mass, B symptom, hepatic deysfunction, and infiltrating surrounding organs significantly affect long term survival.

     

    • HTML全文
    • 参考文献(9)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回