肺癌干细胞的影响机制研究进展

李小江; 张文治; 张莹; 李宝乐; 黄敏娜; 包芳芳; 吴建国; 周佳静; 贾英杰

doi:10.3969/j.issn.1000-8179.2012.09.032

肺癌干细胞的影响机制研究进展

doi: 10.3969/j.issn.1000-8179.2012.09.032

李小江^①,
张文治^②,
张莹^①,
李宝乐^③,
黄敏娜^①,
包芳芳^③,
吴建国^②,
周佳静^③,
贾英杰^①, ,

①.
天津中医药大学第一附属医院肿瘤科（天津市300193）
②.
天津市神经外科研究所细胞生物室
③.
天津中医药大学

基金项目:

国家自然科学基金项目 81001578

详细信息

通讯作者:
贾英杰 jiayingjie1616@sina.com

计量
- 文章访问数: 17
- HTML全文浏览量: 2
- PDF下载量: 1
- 被引次数: 0
出版历程
- 收稿日期: 2011-07-04
- 修回日期: 2011-12-25

Influencing Mechanisms of Lung Cancer Stem Cells

Xiaojiang LI^①,
Wenzhi ZHANG^②,
Ying ZHANG^①,
Baole LI^③,
Minna HUANG^①,
Fangfang BAO^③,
Jianguo WU^②,
Jiajing ZHOU^③,
Yingjie JIA^{①
, ,}

①.
Department of Oncology, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
②.
Tianjin Neurosurgery Institute Cell Biology Room, Tianjin 300060, China
③.
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China

Funds:

the National Natural Science Foundation of China 81001578

More Information

Corresponding author: Yingjie JIA, E-mail: jiayingjie1616@sina.com

摘要

摘要: 肺癌是严重威胁人类生命和健康的恶性肿瘤之一。肿瘤干细胞学说的提出为肺癌研究提供了一个新的思路。多项实验研究已证实了肺癌干细胞的存在。对肺癌干细胞的影响机制的研究日益增多，目前研究主要围绕微环境调控、信号转导机制、细胞因子作用等进行。对肺癌干细胞的影响机制的研究，也为寻求更为有效的治疗方法带来新的希望。
- 肺癌 /
- 干细胞 /
- 机制 /
- 干细胞龛 /
- 信号转导通路
Abstract: Lung cancer is one of the most severe malignant tumors that threaten human health and life. The cancer stem cell theory provides a new research pathway in the field of lung cancer study. The existence of lung cancer stem cells has been confirmed in a few experimental studies. There is an increasing number of studies on the influencing mechanism of lung cancer stem cells, mainly including micro-circumstance regulation, signal transduction mechanisms, and cytokines, bringing new hope for more effective treatments.
- Lung cancer /
- Stem cells /
- Mechanism /
- Stem cell niche /
- Signal transduction pathway

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参考文献(20)

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