白蛋白结合型紫杉醇(Abraxane)联合替吉奥(S-1)一线治疗晚期胃癌的临床观察

Clinical Observation of Advanced Gastric Cancer Treated in Line by Abraxane Combined with S-I

摘要:
目的观察白蛋白结合型紫杉醇(Abraxane)联合替吉奥(S-1)一线治疗晚期胃癌的疗效和安全性。
方法 Abraxane125mg/m², 在化疗的第1和第8天, S-1每天60mg/m², 分2次, 从化疗的第1到第14天; 3周为一个周期, 至少完成2个周期。
结果 19例患者PR11例, SD4例, PD4例, 毒副反应可以耐受。
结论白蛋白结合型紫杉醇作为一种新型紫杉类化疗药联合替吉奥一线治疗晚期胃癌具有广阔研究前景。

Abstract:
Objective To observe the effect and security of advanced gastric cancer treaded in line by Abraxane combined with S-1.
Methods The usage of Abraxane 125 mg/m², D1 and D8, the usage of S-1 60mg/m² Bid P. O. D1-14, after three weeks repeated, at least completed 2 cyclical chemotherapies.
Results The cases of PR, SD and PD in 19 patients were 11, 4 and 4 with mild loxicity.
Conclusion Advanced gastric cancer treated in line by Abraxane combined with S-1 will show vast foreground of treatment.