Abstract:
Objective To investigate the preemptive analgesic efficacy of two tramadol administration methods on postoperative breast cancer pain.
Methods Ninety ASAⅠ~Ⅱfemale patients who underwent breast cancer surgery were randomly divided into 3 groups.Group A: Patients were administered 1.5 mg/kg tramadol 10 min before the operation and again 10 min before the end of operation, respectively. Group B: Patients were administered 1.5 mg/kg tramadol 10 min before the operation.Group C: Patients were not administered tramadol at any time.Data on pain, waking time, and side effects were recorded.
Results The Group A visual analog scale(VAS) values were lower than those of Groups B and C 12 h after the operation(P < 0.05).The Group B VAS values were lower than those of Group C 2 h after the operation(P < 0.05).
Conclusion Tramadol preemptive analgesia has significant analgesic effects on patients who have undergone radical breast cancer operations.Combined administration 10 min before the start and the end of the operation has been proven to be the most effective.