Abstract:
Objective This study investigates the effect of adjuvant trans-catheter arterial chemo-embolization (TACE) treatment after radical resectioning of the hepato-cellular carcinoma (HCC) on disease-free and accumulative survivals.
Methods The clinical data of 53 HCC patients who underwent postoperative adjuvant TACE treatment and 64 patients undergoing simple surgery of HCC were collected. The 1-, 2-, 3-, and 5-year disease-free and accumulative survival rates of the patients were retrospectively studied to analyze the effect of auxiliary TACE treatment on disease-free and accumulative survival rates after HCC surgery.
Results The 1-, 2-, 3-, and 5-year disease-free and accumulative survival rates in the group with TACE treatment after resection were 84.9%, 60.4%, 39.6%, and 18.9%, and 98.1%, 86.8%, 69.8%, and 47.2% respectively. The disease-free and accumulative survival rates of the group with simple HCC surgery were 70.3%, 43.8%, 21.9%, and 12.5%, and 87.5%, 71.9%, 50.0%, and 31.3%, respectively. The log-rank test for the two groups were statistically different between the two cases. The COX regression equation results showed that the treatment with radical surgery plus adjuvant TACE is an independent factor that affects the disease-free and accumulate survival rates.
Conclusion TACE treatment after HCC radical surgery is an independent factor that can improve the disease-free and accumulative survival rates of the patients.