Abstract:
Stage Ⅱ nasopharyngeal carcinoma(NPC) has been one of the hot issues in NPC clinical research over the past few years. The five-year overall survival reaches 74%to 87%after conventional two-dimensional radiotherapy, with distant metastasis as the main failure pattern.Concurrent chemo-radiotherapy improves the prognosis of stage Ⅱ NPC in terms of decreasing distant metastasis.The acute and late complications more commonly occur during conventional radiotherapy.The local control, overall survival, and parotid function are improved by intensity-modulated radiotherapy.However, further studies on the participation of concurrent chemotherapy and intensity modulation radiated therapy in stage Ⅱ NPC are warranted.