易俊林, 高黎. 临床Ⅱ期鼻咽癌的治疗进展[J]. 中国肿瘤临床, 2012, 39(24): 2047-2050. DOI: 10.3969/j.issn.1000-8179.2012.24.015
引用本文: 易俊林, 高黎. 临床Ⅱ期鼻咽癌的治疗进展[J]. 中国肿瘤临床, 2012, 39(24): 2047-2050. DOI: 10.3969/j.issn.1000-8179.2012.24.015
Junlin YI, Li GAO. Advances in Treatment of Stage Ⅱ Nasopharyngeal Carcinoma[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2012, 39(24): 2047-2050. DOI: 10.3969/j.issn.1000-8179.2012.24.015
Citation: Junlin YI, Li GAO. Advances in Treatment of Stage Ⅱ Nasopharyngeal Carcinoma[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2012, 39(24): 2047-2050. DOI: 10.3969/j.issn.1000-8179.2012.24.015

临床Ⅱ期鼻咽癌的治疗进展

Advances in Treatment of Stage Ⅱ Nasopharyngeal Carcinoma

  • 摘要: 临床Ⅱ期鼻咽癌的治疗是鼻咽癌临床研究中的一个热点。常规放射治疗下, 5年总生存率达74%~87%, 远处转移为主要的失败原因, 同期化疗可通过降低远处转移率而改善预后。常规放射治疗对正常组织损伤较大。调强放射治疗技术提高了局部控制和总生存率, 同时对腮腺功能起到明显的保护作用。调强放射治疗联合同步化疗的疗效有待进一步研究。

     

    Abstract: Stage Ⅱ nasopharyngeal carcinoma(NPC) has been one of the hot issues in NPC clinical research over the past few years. The five-year overall survival reaches 74%to 87%after conventional two-dimensional radiotherapy, with distant metastasis as the main failure pattern.Concurrent chemo-radiotherapy improves the prognosis of stage Ⅱ NPC in terms of decreasing distant metastasis.The acute and late complications more commonly occur during conventional radiotherapy.The local control, overall survival, and parotid function are improved by intensity-modulated radiotherapy.However, further studies on the participation of concurrent chemotherapy and intensity modulation radiated therapy in stage Ⅱ NPC are warranted.

     

/

返回文章
返回