Abstract:
Objective This study aims to explore the early-stage therapeutic effects of lobaplatin-based thermochemotherapy and embolization via hepatic artery intervention in the treatment of unresectable primary liver cancer.
Methods Thermochemotherapy and embolization were used to treat 20 unresectable primary liver cancer patients.Epirubicin, mitomycin, and lobaplatin were used for thermochemotherapy.The process was repeated once after 40 d to 50 d.After the two treatment periods, the early effects and side effects were observed.
Results Among the 20 cases, 4(20.0%) received excellent efficacy, 7(35.0%) received good effect, 7(35.0%) demonstrated stabilization, and 2 showed advancement, with a total effective rate of 55.0%.The content of alpha fetoprotein dropped by over 50% in 8 cases, among which 2 returned to normal.
Conclusion The use of thermochemotherapy and embolization via hepatic artery intervention is an effective and safe treatment for primary liver cancer.However, the long-term effects of this treatment need further observation.