Abstract:
Objective To examine metastatic gastric cancer patients who underwent surgery after chemotherapy and to determine the factors affecting survival.
Methods Clinical data on metastatic gastric cancer patients who underwent surgery after chemotherapy were retrospectively analyzed. The overall survival data were evaluated through the Kaplan-Meier method, Log-rank test, and Cox hazards regression.
Results The median age was 46 (22~74), and the median overall survival rate (OS) was 19 months (4~59 months). Response to chemotherapy (23.0 m for PR and 14.5 m for SD, P=0.045) and resection of the primary tumor (23.0 and 5.5 m, respectively, P=0.017) affected OS. No single factor was related to OS according to Cox regression.
Conclusion Surgical removal of the primary tumor is recommended for metastatic gastric cancer patients with positive response to chemotherapy and with a primary tumor that can be resected.