骆惊涛, 魏玺, 张仑. 原发性甲状腺淋巴瘤的超声表现病理及其他影像学特征分析[J]. 中国肿瘤临床, 2014, 41(2): 123-126. DOI: 10.3969/j.issn.1000-8179.20131453
引用本文: 骆惊涛, 魏玺, 张仑. 原发性甲状腺淋巴瘤的超声表现病理及其他影像学特征分析[J]. 中国肿瘤临床, 2014, 41(2): 123-126. DOI: 10.3969/j.issn.1000-8179.20131453
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LUO Jingtao, WEI Xi, ZHANG Lun. Primary lymphoma of thyroid gland: sonographic characteristics, histopathologic finding, and other imaging diagnosis analyses[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2014, 41(2): 123-126. DOI: 10.3969/j.issn.1000-8179.20131453
Citation: LUO Jingtao, WEI Xi, ZHANG Lun. Primary lymphoma of thyroid gland: sonographic characteristics, histopathologic finding, and other imaging diagnosis analyses[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2014, 41(2): 123-126. DOI: 10.3969/j.issn.1000-8179.20131453
shu

原发性甲状腺淋巴瘤的超声表现病理及其他影像学特征分析

Primary lymphoma of thyroid gland: sonographic characteristics, histopathologic finding, and other imaging diagnosis analyses

    摘要
  • 摘要:
      目的   探讨分析原发性甲状腺淋巴瘤超声、病理及其他影像学特征，加强临床医师对本病的深入认识。
      方法   回顾性复习天津医科大学肿瘤医院放治的20例经手术病理证实的原发性甲状腺淋巴瘤。对该20例患者的临床、超声、病理及相关CT、MRI特征进行分析。
      结果   20例原发性甲状腺淋巴瘤均为非霍奇金淋巴瘤（Non-Hodgkin lymphoma，NHL）。超声表现为12例甲状腺双叶受累，8例单侧叶受累。主要特征为：甲状腺弥漫性增大，双叶或单侧一叶回声减低，粗糙不均，内可见多个低回声团块，其中16例颈部伴有多发肿大淋巴结。5例表现肿物侵及气管，1例出现食管与气管同时受压。
      结论   原发性甲状腺淋巴瘤的临床及影像学表现缺乏特异性，最后确诊依靠病理学。如临床发现颈部肿物短时间迅速增大，且超声表现为桥本氏甲状腺炎基础上的恶性征象，应考虑到淋巴瘤，及时做针吸或切取活检，以便临床选择恰当的治疗方案。

     

    Abstract:
      Objective   To evaluate the sonographic characteristics of primary lymphoma of the thyroid gland and to analyze histopathologic findings and other imaging features to improve the diagnostic accuracy of this disease.
      Methods   We retrospectively reviewed the records of 20 patients with histologically proven primary lymphoma of the thyroid gland. The clinical, pathologic, sonographic, CT, and MRI features were analyzed.
      Results   Histology revealed non-Hodgkin lymphoma in 20 patients. Ultrasound revealed lateral thyroid lobe disease in 12 cases and the presence of unilateral masses in 8 cases. The main features seen were diffusely enlarged thyroid gland. The lateral or unilateral thyroid lobe was with hypoechoic masses intermingled with echogenic structures. A total of 16 cases showed enlarged lymph nodes, 5 cases showed invasion of trachea, and 1 case involved the trachea and esophagus.
      Conclusion   Primary lymphoma of the thyroid gland usually presents with clinical and sonographic findings mimicking a carcinoma or benign tumor. If clinical features revealed rapidly enlarging neck masses and sonographic characteristics represented by malignant features of Hashimoto thyroiditis, then we should consider lymphoma. However, the final diagnosis depends on histopathology.

     

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