Abstract:
Objective To investigate the clinical characteristics, treatment, and evaluation of the prognosis of syndrome of inappropriate anti-diuretic hormone (SIADH) in lung-cancer patients.
Methods We review the clinical data of six lung cancer cases, including four small cell lung cancer, one adenocarcinoma, and one squamous cell carcinoma, with SIADH complication. All six cases weretreated in our hospital over the past three years.
Results Patients with various serum sodium levels were provided different therapeutic regimens. Symptoms of fatigue and nervous system disorders, plasma sodium, urine sodium, and plasma osmotic pressure were alleviated.
Conclusion SIADH is a common complication of lung cancer, particularly in small lung cancer cases. Electrolyte disturbances indicate poor prognosis, high mortality rate, and delay in treatment because of clinical interest. After a final diagnosis has been made and appropriate treatment has been administered, clinical symptoms were relieved and blood sodium levels were quickly and significantly improved in these patients.