吴唯, 钱立元, 丁波泥, 岳红. 1 368例乳管镜治疗乳管内病变的临床应用经验[J]. 中国肿瘤临床, 2014, 41(4): 254-258. DOI: 10.3969/j.issn.1000-8179.20131704
引用本文: 吴唯, 钱立元, 丁波泥, 岳红. 1 368例乳管镜治疗乳管内病变的临床应用经验[J]. 中国肿瘤临床, 2014, 41(4): 254-258. DOI: 10.3969/j.issn.1000-8179.20131704
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WU Wei, QIAN Liyuan, DING Boni, YUE Hong. Clinical experience on breast fiberoptic ductoscopy from 1 368 reported cases of patients with breast intraductal lesion[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2014, 41(4): 254-258. DOI: 10.3969/j.issn.1000-8179.20131704
Citation: WU Wei, QIAN Liyuan, DING Boni, YUE Hong. Clinical experience on breast fiberoptic ductoscopy from 1 368 reported cases of patients with breast intraductal lesion[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2014, 41(4): 254-258. DOI: 10.3969/j.issn.1000-8179.20131704
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1 368例乳管镜治疗乳管内病变的临床应用经验

Clinical experience on breast fiberoptic ductoscopy from 1 368 reported cases of patients with breast intraductal lesion

    摘要
  • 摘要:
      目的  总结乳管镜(fiberoptic ductoscopy, FDS)治疗乳管内病变临床应用经验。
      方法  回顾性分析中南大学湘雅三医院近10年来使用FDS检查的1 368例乳头溢液病例的临床资料。
      结果  不同性状的溢液FDS诊断有着显著的差异, 血性和浆液性溢液组肿瘤性疾病检出率明显高于水样和乳汁样溢液组; 对于非肿瘤性乳头溢液, FDS下灌洗治疗能取得较好的治疗效果; FDS定位下手术组较传统切除手术组, FDS诊断病理符合率更高(χ2=10.56, P=0.001)。
      结论  FDS不仅是诊断乳头溢液病因的可靠方法, 而且可以对非肿瘤性乳头溢液进行有效的灌洗治疗; 对于肿瘤性疾病引起的乳头溢液, FDS下定位切除手术能够避免手术盲目性, 为病灶的切除提供可靠的帮助。

     

    Abstract:
      Objective  To consolidate ten years of clinical experience on the application of breast fiberoptic ductoscopy (FDS) in breast intra-ductal lesion.
      Methods  The clinical data of 1 368 cases of patients with nipple discharge were retrospectively collected and analyzed.
      Results  Significant differences were observed in the FDS diagnoses of patients with nipple discharge. The rates of tumor detection by FDS diagnosis were significantly higher when bloody and serous nipple discharge was used rather than milky and watery nipple discharge. For non-tumor nipple discharge, local drug perfusion via FDS was an effective treatment. A total of 303 patients had tumor resection or segmentectomy under localization via FDS, and 44 had segmentectomy after breast duct infusion of methylene blue.The diagnostic rate of localization via FDS (97.0%) was higher than that of breast duct infusion of methylene blue (86.4%).
      Conclusion  FDS is an accurate method for diagnosing patients with nipple discharge. In addition, it is also a good local drug perfusion method for patients with breast inflammatory nipple discharge ductoscopy. For patients with tumorous nipple discharge, localization via FDS can help improve the detection of the lesions, which can be removed by surgery.

     

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