Objective  To analyze the clinico-pathological features of intestinal neuroendocrine tumors (NET), as well as the treatment protocols and survival of intestinal NET patients.

  Methods  Clinico-pathological features of 82 intestinal NET patients were retrospectively reviewed.

  Results  The male to female ratio was 1.41:1 in the group of patients, and the mean age was 48.72±13.26. Up to 72 cases were NET, 7 were neuroendocrine cancer, and 3 were mixed adeno-neuroendocrine carcinoma. The most commonly observed organ exhibiting primary lesion of the tumors was the rectum. The overall five-year survival rates were 78% and 80% among all the patients and among the NET patients, respectively. Tumors of different histological types demonstrated statistically significant differences in terms of primary site, pT stage, and metastasis (P<0.05). The pT stage, histological classification, age, and primary site of the tumors were associated with the metastasis of the intestinal NETs (P<0.05). Age was the main risk factor of metastasis in the tumors.

  Conclusions  Intestinal neuroendocrine neoplasms usually occur in males, and the most commonly involved organ is the rectum. Age is an important factor of neuroendocrine tumor metastasis.