采用保留乳腺方式治疗副乳腺癌的临床分析

刘晓; 桑晓旻; 刘红

doi:10.3969/j.issn.1000-8179.20132168

采用保留乳腺方式治疗副乳腺癌的临床分析

doi: 10.3969/j.issn.1000-8179.20132168

刘晓^①,,
桑晓旻^②,
刘红^①, ,

①.
天津医科大学肿瘤医院乳腺二科，国家肿瘤临床医学研究中心，乳腺癌防治教育部重点实验室，天津市肿瘤防治重点实验室（天津市 300060）
②.
天津市大港油田总医院（天津市 300060）

详细信息

作者简介:
刘晓硕士研究生。研究方向为乳腺癌的早期诊断及综合治疗。E-mail：liuxiaojiayou@126.com

通讯作者:
刘红 E-mail:lh713@163.com

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出版历程
- 收稿日期: 2013-12-20
- 修回日期: 2014-01-22
- 刊出日期: 2014-04-15

Clinical analysis of accessory breast cancer treatment using breast-conserving surgery

LIU Xiao^{①
,},
SANG Xiaomin^②,
LIU Hong^{①
, ,}

①.
The Second Department of Breast Cancer, Tianjin Treatment and Prevention Research Center for Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin 300060
②.
Department of General Surgery, Dagang Oil Field Hospital, Tianjin 300000, China

More Information

Corresponding author: Hong LIU; E-mail:lh713@163.com

摘要

摘要: 目的探讨采用保留乳腺手术方式治疗副乳癌的相关注意事项及预后。方法收集从2003年9月至2013年6月天津医科大学肿瘤医院收治的副乳腺癌患者23例，分析采用不同手术方式治疗副乳腺癌的术前检查、术后治疗及预后。结果采用保留同侧乳腺手术方式的10例患者术前均行乳腺相关检查，证实双乳未见恶性病灶。术后3例行放疗，接受放疗的患者均有不同程度放射性皮炎的发生。随访至2013年10月，2例出现骨转移。13例采用乳腺癌根治术中1例出现肺转移。结论副乳腺癌确诊时，如双侧乳腺未及异常，可采用保留同侧乳腺治疗副乳腺癌的手术方式，术后放疗应注意放射性皮炎发生的可能。
- 副乳腺癌 /
- 保乳手术 /
- 放射治疗
Abstract: Objective To explore matters related to prognosis and treatment of accessory breast cancer using breast-conserving surgery. Methods Retrospective analysis was carried out on the clinical data of 23 patients who underwent two different modes of surgery and were admitted to Tianjin Medical University Cancer Institute and Hospital and Dagang Oil Field Hospital from September 2003 to July 2013. Results No sign of accessory breast cancer was shown by clinical examination, mammography, and ultrasonography of the breast in all 10 cases of surgery without breast removal. Three patients underwent postoperative radiotherapy, and all three showed radiodermatitis in different degrees. Follow-up results revealed that two out of the ten patients who underwent surgery without breast removal had bone metastasis, whereas one of the other 13 had pulmonary metastasis. All patients are still alive as of October 2013. Conclusion Accessory breast cancer treatment without ipsilateral breast removal is viable if no sign of the disease is evident in the breast, and possible signs of radiodermatitis can be expected.
- accessory breast cancer /
- breast-conserving surgery, /
- radiation therapy

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表 1 两组病例临床特点，术后治疗及预后的基本情况例（% ）

Table 1. Clinico-pathological characteristics, radiotherapy, and prognosis of the two groups n(%)

参考文献(16)

[1]	Kitamura K, Kuwano H, Kiyomatsu K, et al. Mastopathy of the accessory breast in the bilateral axillary regions occurring concurrently with advanced breast cancer[J]. Breast Cancer Res Treat, 1995, 35(2):221-224.
[2]	Devine C, Courtney CA, Deb R, et al. Invasive lobular carcinoma arising in accessory breast tissue[J]. World J Surg Oncol, 2013, 11 (1):47. doi: 10.1186/1477-7819-11-47
[3]	Nihon-Yanagi Y, Ueda T, Kameda N, et al. A case of ectopic breast cancer with a literature review[J]. Surg Oncol, 2011, 20(1):35-42. doi: 10.1016/j.suronc.2009.09.005
[4]	Shioi Y, Nakamura S, Kawamura S, et al. Nipple adenoma arising from axillary accessory breast: a case report[J]. Diagn Pathol, 2012, 7(1):162. doi: 10.1186/1746-1596-7-162
[5]	Hao JY, Yang CC, Liu FF, et al. Accessory breast cancer occurring concurrently with bilateral primary invasive breast carcinomas: a report of two cases and literature review[J]. Cancer Biol Med, 2012, 9 (3):197-201. doi: 10.7497/j.issn.2095-3941.2012.03.008
[6]	Val-Bernal JF, González-Vela MC, De Grado M, et al. Sclerotic fibroma (storiform collagenoma)-like stroma in a fibroadenoma of axillary accessory breast tissue[J]. J Cutan Pathol, 2012, 39(8):798-802. doi: 10.1111/j.1600-0560.2012.01940.x
[7]	周文学, 杨维良.副乳腺癌的诊断和治疗(附12例报告)[J].中国普通外科杂志, 1997, 6(1):32- 34. Zhou WX, Yang WL. Diagnosis and treatment of accessory breast cancer(a report of 12 cases)[J]. Chin J Gen Surg, 1997, 6(1):32-34.
[8]	吕民豪, 李永峰, 毛晓韵, 等.副乳腺癌1例报道并文献复习[J].中国普外基础与临床杂志, 2012, 18(11): 1212-1213. Lv MH, Li YF, Mao XY, et al. Report of 1 Case of Accessory Breast Cancer and Literature Review[J]. Chin J Bases Clin General Surg, 2011, 18(11):1212-1213.
[9]	Yamamura J, Masuda N, Kodama Y, et al. Male Breast Cancer Originating in an Accessory Mammary Gland in the Axilla: A Case Report[J]. Case Rep Med, 2012(2011):286210. http://cn.bing.com/academic/profile?id=14bd50f58ac1667846fd1e0a7a96fa04&encoded=0&v=paper_preview&mkt=zh-cn
[10]	Yerra L, Karnad AB, Votaw ML. Primary breast cancer in aberrant breast tissue in the axilla[J]. South Med J, 1997, 90(6): 661-662. doi: 10.1097/00007611-199706000-00018
[11]	Nakao A, Saito S, Inoue F, et al. Ectopic breast cancer: a case report and review of the Japanese literature[J]. Anticancer Res, 1998, 18 (5B):3737-3740. http://cn.bing.com/academic/profile?id=ab2b818987c8ba31494b75babef6e4f8&encoded=0&v=paper_preview&mkt=zh-cn
[12]	Markopoulos C, Kouskos E, Kontzoglou K, et al. Breast cancer in ectopic breast tissue[J]. Eur J Gynaecol Oncol, 2000, 22(2):157-159. http://cn.bing.com/academic/profile?id=eff5bd43f67d443245991c8f491ab40d&encoded=0&v=paper_preview&mkt=zh-cn
[13]	赵东兵, 邵永孚, 周志祥.腋下副乳腺癌12例报告[J].中国实用外科杂志, 2000, 20(5):295-295. doi: 10.3321/j.issn:1005-2208.2000.05.028 Zhao DB, Shao YF, Zhou ZX. Accessory breast cancer:report of 12 cases[J]. Chinese Journal of Practical Surgery, 2000, 20(5):295-295. doi: 10.3321/j.issn:1005-2208.2000.05.028
[14]	Marshall MB, Moynihan JJ, Frost A, et al. Ectopic breast cancer: case report and literature review[J]. Surg Oncol, 1994, 3(5):295-304. doi: 10.1016/0960-7404(94)90032-9
[15]	安松林, 方志沂, 刘君, 等.副乳腺癌17例临床病理分析[J].肿瘤防治研究, 2005, 32(11):721-723. doi: 10.3321/j.issn:1005-2208.2000.05.028 An SL, Fang ZY, Liu J, et al. Clinicopathological Analysis of 17 Cases of Accessory Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2005, 32(11):721-723. doi: 10.3321/j.issn:1005-2208.2000.05.028
[16]	Jensen JM, Gau T, Schultze J, et al. Treatment of acute radiodermatitis with an oil-in-water emulsion following radiation therapy for breast cancer[J]. Strahlenther Onkol, 2011, 187(6):378-384. doi: 10.1007/s00066-011-2224-8