原发性食管小细胞癌的诊疗进展

申威; 邓文英; 李宁; 罗素霞

doi:10.3969/j.issn.1000-8179.20140726

原发性食管小细胞癌的诊疗进展

doi: 10.3969/j.issn.1000-8179.20140726

郑州大学附属肿瘤医院，河南省肿瘤医院消化内科（郑州市450000）

详细信息

作者简介:
申威专业方向为消化道肿瘤基础与临床研究。E-mail：shenwayne440@126.com

通讯作者:
罗素霞 shenwayne440@126.com

计量
- 文章访问数: 44
- HTML全文浏览量: 3
- PDF下载量: 7
- 被引次数: 0
出版历程
- 收稿日期: 2014-05-04
- 修回日期: 2014-08-20
- 刊出日期: 2020-12-29

Advances in diagnosis and management of primary esophageal small cell carcinoma

Department of Gastroenterology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450000, China

More Information

Corresponding author: Suxia LUO; E-mail: shenwayne440@126.com

摘要

摘要: 食管小细胞癌（primary esophageal small cell carcinoma，PESCC）是一种恶性程度高、易远处转移、预后极差的罕见疾病，近年来，国内外食管小细胞癌的发病率呈明显上升趋势。食管小细胞癌是一种最常见的消化道小细胞癌，但其生物学行为、治疗模式及预后均不同于食管鳞癌，国内外尚无关于PESCC的前瞻性随机对照研究。目前临床中对于其组织来源、诊断方式、治疗模式及预后因素尚未形成共识。为加深对PESCC的理解和更好地解决临床问题，本文就近年来食管小细胞癌的相关诊疗进展及不同见解作一综述。
- 小细胞癌 /
- 食管癌 /
- 手术 /
- 放疗 /
- 化疗 /
- 靶向治疗 /
- 预后
Abstract: Primary esophageal small cell carcinoma (PESCC) is a rare disease first described by McKeown in 1952. PESCC is characterized by high malignancy, distant metastasis, and poor prognosis. The incidence of PESCC has significantly increased worldwide in recent years. However, practice guidelines that concern the histological origin, clinical diagnosis methods, therapies, and prognosis of PESCC are still not well established because of the paucity of cases and lack of large prospective randomized research. This article aims to outline recent advances in the clinical and therapeutic aspects of PESCC as well as review the different opinions concerned to better understand PESCC and solve clinical problems.
- small cell carcinoma /
- esophageal cancer /
- surgery /
- radiotherapy /
- chemotherapy /
- targeted therapy /
- prognosis

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参考文献(40)

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