Abstract: Objective:To investigate the recognition and injury prevention strategies of hepatic artery variations during hepatic portal lymphadenectomy. Methods:A retrospective analysis was performed, and12patients of hepatic arterial variation among 62pa -tients with hepatic portal lymphadenectomy were the subjects. The study was conducted in the First Affiliated Hospital of Bengbu Medi -cal College between January 2013and July 2014. The intraoperative treatment and postoperative complications were recorded. Results: Among12cases of hepatic artery variation, we found the following cases: 3 cases ( 25.0%) of Michels' Type III, 2 cases ( 16.7%) of Mi-chels' Type VI,1 case (8.3%) of Michels' Type IX, 1 case (8.3%) of Hiatt's Type6, 2 cases ( 16.7%) of spatial location variation between right hepatic artery and hepatic duct, 2 cases ( 16.7%) of left and right hepatic artery originating from a common hepatic artery, and1 case (8.3%) of right hepatic artery originating from the gastroduodenal artery. No injury of hepatic artery occurred. Two cases had post -operative complications, including 1 case of pancreatic leakage and 1 case of incision infection; postoperative hemorrhage, bile leakage, hepatic abscess did not occur in these two cases. Patients recovered well in general. Conclusion: Hepatic arterial injury can be signifi -cantly reduced by the following: increased familiarity with the various types of hepatic artery variations; complete imaging examina -tions for inspection and evaluation before surgery; and careful and meticulous operations in surgery.