赵玲娣, 高全立. CAR-T 细胞在肿瘤治疗中的研究进展[J]. 中国肿瘤临床, 2015, 42(3): 190-194. DOI: 10.3969/j.issn.1000-8179.20141675
引用本文: 赵玲娣, 高全立. CAR-T 细胞在肿瘤治疗中的研究进展[J]. 中国肿瘤临床, 2015, 42(3): 190-194. DOI: 10.3969/j.issn.1000-8179.20141675
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Lingdi ZHAO, Quanli GAO. Research progress of CAR T-cell in tumor therapy[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2015, 42(3): 190-194. DOI: 10.3969/j.issn.1000-8179.20141675
Citation: Lingdi ZHAO, Quanli GAO. Research progress of CAR T-cell in tumor therapy[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2015, 42(3): 190-194. DOI: 10.3969/j.issn.1000-8179.20141675
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CAR-T 细胞在肿瘤治疗中的研究进展

Research progress of CAR T-cell in tumor therapy

    摘要
  • 摘要: 以嵌合型抗原受体（chimeric antigen receptor，CAR ）为基础的细胞免疫治疗是一种新的治疗恶性肿瘤的模式，为部分晚期实体瘤患者带来治愈的希望。选择合适的目标靶分子、应用安全的基因转导方法、防治CAR-T细胞治疗的不良反应、将使CAR-T细胞造福越来越多的晚期肿瘤患者。

     

    Abstract: Adoptive cell transfusion based on chimeric antigen receptor (CAR) is a new approach for treating malignant diseases and even advanced malignancies. More patients with advanced malignancies are expected to benefit from CAR T-cells once the suitable target molecules are selected, the safe method of gene transduction is applied, and the side effects of CAR T-cells are prevented.

     

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