Abstract: Objective:To discuss the significance of standardized treatment for cancer pain, according to the Cancer Pain Treat -ment Specification (2011 Edition) issued by the Ministry of Health, PR China.Methods:Clinical data of126 patients with cancer pain, who were admitted to the Department of Medical Oncology, The Fourth Hospital of Hebei Medical University, were collected to com-pare the improvement of the Numeric Rating Scale (NRS) score, number of breakthrough pain, and quality of life score after treatment. The relationships between different pain grades, disease entities, and treatment effect were analyzed. The influence factors of pain relief were also analyzed by using Logistic regression analysis.Results: 1). Following standardized treatment, the improvement rate of NRS score has shown significant differences in pain grading (P=0.001) and gender ( P=0.000). However, no significant differences were ob -served between different diseases (P=0.112). The improvement rate of the life quality score and the number of breakthrough pain had no significant difference after standardized treatment. 2). The grading of cancer pain and the disease entities had little effect on cancer pain relief. 3). The anti- tumor treatment and“no distant metastasis”were the independent factors that brought about the decrease in NRS and quality of life scores. “No distant metastasis ”(P=0.046) was the independent factor that reduced the number of pain out breaks. Conclusion:The standardized treatment positively affects the NRS score, number of breakthrough pain, and quality of life score. Patients who received anti- neoplastic therapy and who had no distant metastasis showed significant treatment effectiveness in pain management.