胃癌患者术前CRP/Alb比与淋巴结转移相关性的研究

乔乐乐; 王公平; 周博; 金灿辉; 汪增方; 杨言通; 智鹏柯; 陈晔; 解延飞; 冯笑山

doi:10.3969/j.issn.1000-8179.2017.05.246

胃癌患者术前CRP/Alb比与淋巴结转移相关性的研究

Correlation between preoperative CRP/Alb ratio and lymph node metastasis in patients with gastric cancer

摘要

摘要:
目的探讨胃癌患者术前CRP/Alb比（CAR）与淋巴结转移的关系。
方法选取2013年10月至2016年9月河南科技大学第一附属医院收治的96例胃癌患者，以术前CAR为因变量对胃癌患者临床病理分期及术中淋巴结检出情况进行分析。
结果 1）术前CAR≤0.04与CAR>0.04的患者比较，后者有更高的转移率和转移度，且差异有统计学意义（P < 0.05）。术前CAR>0.04组的患者中，淋巴结分期>N0者明显多于术前CAR≤0.04组，且差异有统计学意义（P < 0.05）。2）Borrmann分型Ⅰ、Ⅱ、Ⅲ、Ⅳ型患者的CAR均逐渐增高；随着胃癌病理分期的进展，CAR均值增高。3）术中淋巴结清扫总数较多组，其术前CAR均值偏高。
结论胃癌患者术前CAR的高低与淋巴结转移之间具有相关性，可以在一定程度上反映淋巴结转移的程度。

Abstract:
Objective To investigate the relationship between Creactive protein (CRP)/albumin ratio (CAR) and lymph node metastasis of gastric cancer.
Methods A total of 96 cases of gastric cancer were included in the study. The clinical pathological stage and lymph node detection in patients with gastric cancer were analyzed, with the preoperative CAR as the dependent variable.
Results 1) The patients with preoperative CAR > 0.04 has higher transfer rate and metastasis than the patients with preoperative CAR≤0.04, and the difference was significant (P < 0.05). The lymph node stage of patients with preoperative CAR > 0.04 was significantly higher than that of the patients with preoperative CAR≤0.04, and the difference was significant (P < 0.05). 2) The mean CAR of patients with Borrmann types Ⅰ, Ⅱ, Ⅲ, and Ⅳ gradually increased; with the progression of the pathological stage of gastric cancer, the mean value of CAR increased. 3) During the operation, the total number of lymph node dissections was high and the mean value of CAR before the operation was high.
Conclusion The correlation between preoperative CAR and lymph node metastasis in patients with gastric cancer may reflect the degree of lymph node metastasis to a certain extent.

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