EBV相关性胃癌中EB病毒基因表达研究进展

Research progress on expression of Epstein-Barr virus genes in EBV associated gastric carcinoma

摘要: EB病毒（Epstein-Barr virus，EBV）是胃癌发生的生物学病因之一，EBV相关性胃癌（EBV associated gastric carcinoma，EB-VaGC）具有独特的临床病理学特征，其预后相对较好，因此EBV导致胃癌的机制研究也备受关注。近年来，随着分子生物学技术的发展，EBVaGC组织中EBV病毒基因表达的研究逐渐增多，为EBVaGC的诊断、治疗和预防提供了一定的理论依据。本文就EBVaGC组织中EBV病毒基因的表达进行综述。

Abstract: Epstein-Barr virus (EBV) is a biological factor associated with gastric carcinoma. The prognosis of EBV-associated gastric carcinoma (EBVaGC) is good because of its distinct clinicopathological features. The pathogenesis mechanism of EBVaGC is extensively investigated at present. The development of molecular techniques has stimulated the research on the expression of EBV genes in EBVaGC, thereby providing a theoretical foundation on the diagnosis, therapy, and prevention of EBVaGC. This article reviewed present research advances in EBV genes in EBVaGC.