Abstract:
Objective To discuss treatment of complete response cases after neoadjuvant radiotherapy in rectal cancer.
Methods This retrospective study analyzed clinical data of 84 rectal cancer cases with pre-operative neoadjuvant chemoradiotherapy in our hospital from January 2010 to Augnst 2014.
Results After neoadjuvant chemoradiotherapy, 33 patients presented clinically complete response at a rate of 39.3%. After post-operative pathologic examination, among clinically complete response cases, six cases exhibited pathologically complete responses at a rate of 18.2%. No recurrence or disease progression occurred within 12-36 months of post-operative follow up.
Conclusion Neoadjuvant chemoradiotherapy can significantly lower tumor stage and promote clinically complete remission of some patients. However, for clinically complete remission cases, further radical surgery should be provided.