Abstract:
Objective This study aimed to compare the short-and long-term outcomes of laparoscopy-assisted radical gastrectomy between elderly and non-elderly patients with gastric cancer.
Methods A total of 219 patients who underwent laparoscopy-assisted radical gastrectomy in the Department of Gastrointestinal Surgery Ⅳ, Peking University Cancer Hospital & Institute from April 2009 to October 2013 were included in this retrospective study. All patients were divided into elderly (≥65 years) and non-elderly ( < 65 years) groups. We compared these groups based on clinicopathological characteristics, postoperative morbidities, and survival.
Results Theelderly group showed higher ASA scores and higher number of preoperative comorbidities (P < 0.05). The operative time, blood loss, and conversion rate did not differ significantly between the groups (all P > 0.05). The mean time to first ambulation in elderly group was 2.2±2.3d while first ambulation time in the non-elderly group was 1.4±1.3d, which showed significant difference between the two groups (P < 0.05). No significant differences were observed between groups in terms of postoperativemorbidities (34.8% vs. 28.5%, P > 0.05) as well as 3-year disease-free survival and overall survival (P > 0.05). However, the elderly patients withpostoperative morbidities experienced significantly poorer overall survival rate than non-elderly patients (44.5% vs. 70.5%, P < 0.05).
Conclusion Laparoscopy-assisted gastrectomy can be safely and successfully performed in an elderly population with acceptable short-and long-term outcomes. Enhanced perioperative treatment is necessary to improve postoperative outcomes.
下载: