直肠癌伴同时性多发性肺转移患者的多学科临床决策探讨

Multidisciplinary decision on a rectal cancer patient with multiple synchronous pulmonary metastasis

摘要: 结直肠癌患者中肺是继肝脏之后最常见的远处转移器官之一，但由于肺转移发病率较低且生物学侵袭性相对温和，因而与结直肠癌肝转移相比，结直肠癌肺转移无论是关注程度、综合治疗理念还是相关的临床和基础研究都相对匮乏。本文现介绍1例直肠癌伴同时性多发性肺转移患者在浙江大学医学院附属第二医院大肠癌诊治中心的多学科综合治疗(multidisciplinary team，MDT)经过，以探讨该类患者的临床病理特征、预后影响因素、合理的综合治疗决策以及现有的诊治争议与共识，以期促进临床诊疗的规范化和个体化，使患者更多获益。

Abstract: Lungs are the second most common distant metastatic organs of colorectal cancer, following the liver. However, clinical researches on lung metastasis are insufficient comparing with that on liver metastasis due to its low occurrence and relatively mild biological behavior. This paper aims to investigate the clinicopathological characteristics and prognostic factors of rectal cancer patients with multiple synchronous lung metastases. The patient was from the Second Affiliated Hospital of Zhejiang University, School of Medicine underwent multi-disciplinary diagnosis and treatment. Moreover, this article aims to discuss the related existing consensus and controversies on this issue.