早期胃癌内镜黏膜下剥离术的现状及应用进展

吴亮亮; 梁寒

doi:10.3969/j.issn.1000-8179.2019.05.048

早期胃癌内镜黏膜下剥离术的现状及应用进展

doi: 10.3969/j.issn.1000-8179.2019.05.048

吴亮亮,
梁寒^,

天津医科大学肿瘤医院胃部肿瘤科，国家肿瘤临床医学研究中心，天津市肿瘤防治重点实验室，天津市恶性肿瘤临床医学研究中心（天津市300060）

基金项目:

重大慢性非传染性疾病防控研究项目 2016YFC1303202

国家重点研发计划“精准医学研究”计划项目 2017YFC0908300

详细信息

作者简介:
吴亮亮专业方向为胃肠道恶性肿瘤的基础研究及临床治疗。E-mail：wulaingliang830906@126.com

通讯作者:
梁寒 prof_lianghan@126.com

计量
- 文章访问数: 58
- HTML全文浏览量: 26
- PDF下载量: 8
- 被引次数: 0
出版历程
- 收稿日期: 2019-01-10
- 修回日期: 2019-03-05
- 刊出日期: 2019-05-15

Current status and application of endoscopic submucosal dissection for early gastric cancer

Wu Liangliang,
Liang Han^,

Department of Gastric Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China

Funds:

National Key Research and Development Program of Major Chronic Non-infectious Disease Prevention and Control Research 2016YFC1303202

National Key Research and Development Program "Precision Medicine Research" Program 2017YFC0908300

More Information

Corresponding author: Han Liang; E-mail:prof_lianghan@126.com

摘要

摘要: 随着内镜治疗技术的发展，新的内镜下治疗器械的不断开发和应用以及人们健康意识的提高，越来越多的胃癌在早期阶段即被发现。开腹手术与腹腔镜手术治疗早期胃癌（early gastric cancer，EGC）均可取得令人满意的疗效。为提高患者术后生存质量以及降低并发症，早期胃癌在内镜下治疗逐渐被广泛应用。内镜黏膜下剥离术（endoscopic submucosal dissection，ESD）在EGC诊疗中的应用越来越广泛，其5年总生存率可达90%；治疗效果具有创伤小、安全性高、患者依从性好、治疗成本低等特点。ESD有可能逐渐取代传统的外科手术，成为早期胃癌的主要治疗手段。本文就ESD在EGC中的临床应用进展进行综述。
- 早期胃癌 /
- 内镜黏膜下剥离术 /
- 并发症
Abstract: Owing to technological developments in endoscopic treatment with continued development and application of newer endoscopic equipment, as well as improved health consciousness among patients, a greater number of patients are being diagnosed with early gastric cancer (EGC). Both laparotomy and laparoscopic surgery can achieve satisfactory results in the treatment of EGC. Patients undergoing endoscopic treatment for EGC showed improved quality of life postoperatively with lower complication rates. Endoscopic submucosal dissection (ESD) is being widely used to treat EGC, with an overall 5-year survival rate of 90%. Patients undergoing ESD showed better perioperative outcomes in terms of lesser physical trauma, higher safety, excellent patient compliance, and lower treatment costs. ESD may gradually replace conventional surgery as the primary treatment for EGC. This paper focuses on the clinical application of ESD in the management of EGC.
- early gastric cancers (EGC) /
- endoscopic submucosal dissection (ESD) /
- complication

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参考文献(45)

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