杨鑫苗, 张永强. 乳腺癌合并皮肤转移的治疗进展[J]. 中国肿瘤临床, 2019, 46(23): 1237-1240. DOI: 10.3969/j.issn.1000-8179.2019.23.390
引用本文: 杨鑫苗, 张永强. 乳腺癌合并皮肤转移的治疗进展[J]. 中国肿瘤临床, 2019, 46(23): 1237-1240. DOI: 10.3969/j.issn.1000-8179.2019.23.390
Yang Xinmiao, Zhang Yongqiang. Advances in the treatment of breast cancer with cutaneous metastasis[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2019, 46(23): 1237-1240. DOI: 10.3969/j.issn.1000-8179.2019.23.390
Citation: Yang Xinmiao, Zhang Yongqiang. Advances in the treatment of breast cancer with cutaneous metastasis[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2019, 46(23): 1237-1240. DOI: 10.3969/j.issn.1000-8179.2019.23.390

乳腺癌合并皮肤转移的治疗进展

Advances in the treatment of breast cancer with cutaneous metastasis

  • 摘要: 恶性肿瘤的皮肤转移相对少见,乳腺癌是女性最常见合并皮肤转移的恶性肿瘤。大部分皮肤转移的乳腺癌均合并其他部位转移,也有少数患者以皮肤转移为首发或唯一表现。单发或少发局限于胸壁的结节型皮肤转移病灶,通过局部为主的综合治疗,部分患者有望获得长期生存或临床治愈;而广泛的皮肤转移以及合并内脏、骨转移的皮肤转移患者,临床上难以治愈,预后不佳,系统治疗联合局部治疗可以减轻肿瘤负荷、缓解痛苦、改善患者生存质量。本文将就乳腺癌合并皮肤转移基本特征及治疗进展进行综述。

     

    Abstract: Cutaneous metastasis from malignant tumors are relatively rare. Breast cancer is the most common malignant tumor with cutaneous metastasis in women. Most breast cancers with skin metastases also show metastasis to other areas in the body, and few patients present with skin metastases as the first or only manifestation. Through local comprehensive treatment, some patients with a single metastasis or few nodular skin metastases confined to the chest wall are expected to achieve long-term survival or clinical cure. However, other patients with extensive skin metastasis or skin metastases accompanied by internal organ and/or bone metastasis are difficult to treat and thus, have a poor prognosis of survival. The combination of systematic and local treatment can reduce the metastatic potential of the tumor along with its burden, as well as relieve patients' pain and improve their overall survival. Thus, we focus on reviewing the basic characteristics of skin metastasis associated with breast cancer and the advancements in treatment reported in the recent literature.

     

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