Abstract:
Cutaneous metastasis from malignant tumors are relatively rare. Breast cancer is the most common malignant tumor with cutaneous metastasis in women. Most breast cancers with skin metastases also show metastasis to other areas in the body, and few patients present with skin metastases as the first or only manifestation. Through local comprehensive treatment, some patients with a single metastasis or few nodular skin metastases confined to the chest wall are expected to achieve long-term survival or clinical cure. However, other patients with extensive skin metastasis or skin metastases accompanied by internal organ and/or bone metastasis are difficult to treat and thus, have a poor prognosis of survival. The combination of systematic and local treatment can reduce the metastatic potential of the tumor along with its burden, as well as relieve patients' pain and improve their overall survival. Thus, we focus on reviewing the basic characteristics of skin metastasis associated with breast cancer and the advancements in treatment reported in the recent literature.