Abstract: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death in China and one of the major health problems worldwide.Although significant progress has been made in the early detection and treatment of cancer, the mortality rate remains high in most countries.The prognosis of HCC patients depends not only on tumor characteristics but also on individual differences related to etiology, liver function, and patient characteristics.Although several prognostic models for liver cancer have been proposed worldwide, these models have shown varying abilities in terms of determining the prognosis of liver cancer.Therefore, it is important to compare and analyze the abilities of these prognostic models in terms of liver cancer prognosis and treatment guidance. The purpose of this review was to analyze and compare the advantages and disadvantages of eight common prognostic models (Okuda, TNM8, BCLC, JIS, CUPI, CLIP, GRETCH, and CIS) to provide new ideas for future clinical and scientific research.