Abstract: Objective: To investigate the clinical characteristics, treatment, and prognosis of brain metastasis from epithelial ovarian cancer. Methods: We retrospectively reviewed the clinical data from 7 patients with brain metastasis of epithelial ovarian cancer seen in our hospital from January 1986 to March 2007. We also reviewed literature on this topicpublished within the past 5 years. Results: All 7 patients seen in our hospital were at stage Ⅲ～ Ⅳ when they were initial-ly diagnosed. Three cases were identified as serous adenocarcinoma, the most common type. Three cases had solitarymetastatic lesions in the brain, and the other 4 cases had multiple metastatic lesions. Four cases had extracranial metastat-ic lesions. The interval between the initial diagnosis and the detection of metastases in the brain was 20.0~32.7 months. Atotal of 160 cases of brain metastasis from epithelial ovarian cancer has been reported in the past 5 years. Seventy-eight(49.0%) of the 160 patients were identified with serous adenocarcinoma. At the initial diagnosis, 17.0% of them were stageⅠ or Ⅱ cancers, and 83.0% were stage Ⅲ or Ⅳ cancers. There were solitary metastatic lesions in the brain in 53.4%.The interval between the initial diagnosis and detection of metastases in the brain was 14.4~42.0 months. Extracranialmetastases were detected in 55.0% of the patients. Headache and vomiting were the most common clinical manifestations.Serum CA125 level was valuable in evaluating and monitoring the state of the disease. The mean survival was 7.9~16.1months in the 7 patients we reviewed and 15.9~4 months in the 160 patients from the literature. Conclusion: Brain metas-tases from epithelial ovarian cancer are uncommon and suggest a poor prognosis. Such patients should be evaluated com-prehensively before undergoing individual treatment. Combined use of radiotherapy and chemotherapy is effective.