Abstract: Objective : Pleural biopsy plays an important role in the differential diagnosis of pleural disease. Thoughpleural biopsies using Vim-Silverman type needle, Abrams needle, Cope needle, Tru-Cut needle, video-assist-ed thoracoscope and bronchofibroscope are popular in obtaining pleural tissues, these methods have somedisadvantages. The tissue obtained is small, the procedures are complicated, and they may cause trauma.The aim of this study is to evaluate the feasibility and safety of using trocar forceps, a new technique for pleu-ral biopsy. Methods : Thirty patients with pleural effusion underwent parietal pleura biopsy at the anterior axil-lary line. We inserted the trocar into the pleural cavity perpendicularly, pulled off the core-needle, inserted thebiopsy forceps into the canula, and then held the canula with one hand and carefully pinched the body of thebiopsy forceps with the other hand. We then opened the biopsy forceps, gently pushing both the canula andthe biopsy forceps to increase pressure against the pleura and ultimately closed the forceps to pull off the tis-sue sample. Results : Pleural tissue was successfully obtained in 29 patients (96.6%), 21 (70.6%) of which con-firmed the pathological diagnosis of the first biopsy. In 16 patients (76.2%), a definitive diagnosis was madeon the basis of the first biopsy. Neither muscle nor fat was observed microscopically. The average size of tis-sue sample obtained using trocar forceps was 2.1±1.3mm. Pneumothorax occurred in 4 patients (13.3%).Fourteen (46.6%) patients had pleuralgia and 3 patients had hemorrhage (10%). Conclusion : Parietal pleuralbiopsy with trocar forceps is simple, safe and effective.