Abstract: Objective: To observe the expression of S100A9 and Galectin7 in cervical carcinoma tissues with differ-ent concurrent chemoradiotherapy sensitivity and to analyze its significance. Methods: The fresh carcinoma tissues werecollected from 10 untreated cervical carcinoma patients. According to the response to concurrent chemoradiotherapy, thetissues were classified into two groups: the high sensitivity group(HS) and the low sensitivity group(LS). Protein separationwas performed by two-dimensional gel electrophoresis (2-DE). The peptide mass fingerprintings (PMF) were acquired bymatrix assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF-MS) and the proteins were iden-tified by data searching in the Mascot-database. The differentially expressed proteins were assayed by Western blot andimmunohistochemistry. Results: Most of the gels were clear and successfully and reproductively analyzed. It showed thatthe expression of S100A9 and Galectin7 was higher in the HS group than in the LS group. Conclusion: The expression ofS100A9 and Galectin7 was associated with concurrent chemoradiotherapy sensitivity in cervical carcinoma.