王玉, 景娜. 早期乳腺癌术后放疗的临床分析[J]. 中国肿瘤临床, 2004, 31(15): 854-855,859.
引用本文: 王玉, 景娜. 早期乳腺癌术后放疗的临床分析[J]. 中国肿瘤临床, 2004, 31(15): 854-855,859.
Wang Yu, Jing Na. Postoperative Raaiotherapy lor Early Breast Cancer[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 31(15): 854-855,859.
Citation: Wang Yu, Jing Na. Postoperative Raaiotherapy lor Early Breast Cancer[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 31(15): 854-855,859.

早期乳腺癌术后放疗的临床分析

Postoperative Raaiotherapy lor Early Breast Cancer

  • 摘要: 目的:探讨早期乳腺癌根治术,仿根治术后的放疗剂量及照射范围。方法:对比分析本院1980年3月~1993年3月收治的T2N1M0期乳腺癌术后放疗者418例(放疗组)与术后未行放疗者180例(手术组)。418例中DT≥50Gy者86例,淋巴引流区伴胸壁照射者148例。结果:放疗组中DT≥50Gy者与手术组相比,其中腋淋巴结转移≥4个者的10年生存率分别为66.7%(32/48)与34.5%(10/29),复发率分别为6.3%(3/48)与34.5%(10/29),P均<0.05。放疗组中淋巴引流区伴胸壁照射者148例与手术组相比,其中腋淋巴结转移≥4枚者的10年生存率分别为62.8%(54/86)与34.5%(10/29),复发率分别为4.7%(4/86)与34.5%(10/29),P均<0.05。结论:对腋窝淋巴结转移≥4枚者,术后提高肿瘤剂量达50Gy以上,可降低锁骨区淋巴结转移与胸壁复发。

     

    Abstract: Objective : To study the radiation doses and radiation region for early breast cancer after radical operation and simply modified operation. Methods : Treatment results were compared between 418 stage T NM breast cancer patients who received postoperative radiotherapy (RT) and 180 patients who received operation only (OT) from March 1980 through 1993. 86 cases received radiation doses ≥50Gy (HRT) AND 148 cases received lymphatic drainage regions and chest wall radiation (RCT). Results : The 10-year survival rates and recurrence rates for patients with >4 positive axillay Lymph nodes in HRTgroup and OT group were 66.7%, 34.5%(P<0.05) and 6.3%, 34.5%(P<0.05), respectively; Among the patients who received the postoperative radiation of chest wall and lymphatic drainage region compare with the OT group, the 10-year survival rate and recurrence rate for patients with >4 positive axillary lymph nodes in CRT group and OT group were 62.8%, 34.5% (P<0.05) and 4.7%, 34.5%(P<0.05), respectively. Conclusion : Increasing radiation dose to ≥50Gy can low the recurrence of chest wall and supraclaricular lymph nodes.

     

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