Abstract:
Objective :The aim of this study was to evaluate clinical effects of percutaneous radiofrequency ablation, performed by using a clustered electrode needle, in the treatment of lung metastasis.
Methods :Lung metastases were randomized into radiofrequency ablation group and conventional group. the radiofrequency ablation group received radiofrequency ablation of metastasis lesion, while The conventional group received conventional operation or radiotherapy.
Results The rate of improvement of KPS for patients in the radiofrequency ablation group was superior to the patients in the conventional group (X
2=6.23;
p<0.05). The local recurrent rate in the radiofrequency ablation was less than that in conventional group (18.75%, 43.75%;X
2=4.66;
P<0.05). Median survival times were 20months (95%CI 11-29 months)in the radiofrequency ablation group and 18 months (95%CI 12-24) in the conventional group. There was better one year,two year and three year survival rates for the radiofrequency ablation group comparing with the conventional chemoradiotherpy (76.06%, 69.41%; 39.42%, 26.84%, 23.63%, 17.89%,respectively), but no statistically differences (Log rank, X
2=0.77,
P>0.05).
Conclusions :Radiofrequency ablation by EYB electrode needle can decreased local recurrence and improved performance status for lung metastasis.