赵健, 王远东, 吴一龙, 陈永东, 赵光日, 王建. 射频毁损治疗肺转移瘤的疗效观察[J]. 中国肿瘤临床, 2004, 31(20): 1147-1149.
引用本文: 赵健, 王远东, 吴一龙, 陈永东, 赵光日, 王建. 射频毁损治疗肺转移瘤的疗效观察[J]. 中国肿瘤临床, 2004, 31(20): 1147-1149.
Zhao Jian, Wang Yundong, Wu Yilong, Chen Yongdong, Zhao Guangri, Wang Jian. The Analysis of Percutaneous Radiofrequency Ablation in Therapy of Lung Metastasis[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 31(20): 1147-1149.
Citation: Zhao Jian, Wang Yundong, Wu Yilong, Chen Yongdong, Zhao Guangri, Wang Jian. The Analysis of Percutaneous Radiofrequency Ablation in Therapy of Lung Metastasis[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 31(20): 1147-1149.

射频毁损治疗肺转移瘤的疗效观察

The Analysis of Percutaneous Radiofrequency Ablation in Therapy of Lung Metastasis

  • 摘要: 目的 :探讨经皮肺穿刺射频毁损治疗肺转移瘤的临床疗效。 方法 :对2000年3月~2003年3月本院收治的65例肺转移瘤患者随机分为射频组和常规组;射频组肺转移瘤行经皮肺穿刺射频毁损治疗,常规组给予手术或放疗等常规治疗。 结果 :射频组KPS改善率明显优于常规组(X2=6.23,P<0.05);原发灶局部复发率射频组显著低于常规组(18.75%,43.75%;X2=4.66,P<0.05);中位生存时间射频组20个月(95%CI11~29个月),常规组为18个月(95%CI12~24个月);1、2、3年生存率射频组稍高于常规组(76.06%,69.41%;39.42%,26.84%;23.63%,17.89%),但两组生存曲线比较无统计学意义(Logrank法检验,X2=0.77,P<0.05)。 结论 :经皮肺穿刺射频毁损治疗肺转移瘤比常规治疗手术或放疗局部复发率低,患者的生活质量更高。

     

    Abstract: Objective :The aim of this study was to evaluate clinical effects of percutaneous radiofrequency ablation, performed by using a clustered electrode needle, in the treatment of lung metastasis. Methods :Lung metastases were randomized into radiofrequency ablation group and conventional group. the radiofrequency ablation group received radiofrequency ablation of metastasis lesion, while The conventional group received conventional operation or radiotherapy. Results The rate of improvement of KPS for patients in the radiofrequency ablation group was superior to the patients in the conventional group (X2=6.23;p<0.05). The local recurrent rate in the radiofrequency ablation was less than that in conventional group (18.75%, 43.75%;X2=4.66;P<0.05). Median survival times were 20months (95%CI 11-29 months)in the radiofrequency ablation group and 18 months (95%CI 12-24) in the conventional group. There was better one year,two year and three year survival rates for the radiofrequency ablation group comparing with the conventional chemoradiotherpy (76.06%, 69.41%; 39.42%, 26.84%, 23.63%, 17.89%,respectively), but no statistically differences (Log rank, X2=0.77, P>0.05). Conclusions :Radiofrequency ablation by EYB electrode needle can decreased local recurrence and improved performance status for lung metastasis.

     

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