Abstract:
Objective: To study the relationship of CT enhancement value and microvessel density, p53 protein expression in NSCLC. Methods: CT scan and proteins expression of factor and p53 measured immunohistochemically (S-P method) on 54 cases NSCLC. Microvessel density was calculated by labeling the endothelial cells of the microvessel within the tumor with factor. Results: In 54 NSCLC, CT enhancement value was correlated positively with microvessel density, r=0.6313; the mean value of CT enhancement and microvessel density in of p53 positive group were greater than p53 negative significantly, P<=0.000, P<=0.007. Conclusion: The CT value of enhancement is correlated with microvessel density, and correlated with p53 protein expression too.