Abstract: Objective: To evaluate clinical feature of osseous metastasis in differentiated throid cancer. Methods : To retrospectively analyze the age of osseous metastasis, postoperative interval time, metastatic part and frequency, histological type, death cause and so on in differentiated thyroid cancer. Results : Most of the patients with osseous metastasis were 40 to 85 years old and took place in 10 years from preliminary diagnosis to bone metastasis. Vertebral metastasis occured mostly, and papillary carcinoma took place in dorsal vertebra and cervical vertebra, follicular carcimoma in total body bones. Clinical symptom and death cause were relevant to the vertebral lesion. Conclusions : The vertebra is the important part of the body to affect the living quality and prognosis in differentiated thyroid cancer osseous metastasis.