Abstract: Objective :To observe the effect and side effects of Concurrent chemoradiotherapy for advanced cervical cancer. Methods :Form December 1997 to June 1999,87 patients with advanced cervical cancer were randomly allocated into 2 groups. The synthesis group: the radiotherapy was carried out the same as the conventional fractionation group,i.e. firstly with Cisplatin 20mg iv d1=d%,%-Fluorouracil 750mg iv d1 -5,repeat every 28 days, total 4 cycle; the conventional fractionation group received routine radiotherapy 2Gy per day, 5 times a week to a total does of 30Gy with 192Ir brachyther-apy, 8Gy per week. When total dose reach 46Gy, the middle field is shielded by plumbum,continuous radiotherapy,total dose reach A point 70Gy,B point 56Gy. Results :All patients were followed-up for more than five years .the follow-up rate was 93.0U. In the concurrent chemoradiotherapy group, the 3-year survival rate and the 5 -year survival rate were 86.4U and 65.9U. In the radiotherapy group,the 3-year survival rate and the 5-year survival rate were 55.8U and 39.5U. There is significant difference in two groups (P<0.05,ײ=4.144;5.09), no significant difference in toxicity-side effect. Conclusion :Concurrent chemoradiotherapy for advanced cervical cancer can significantly improve the 3-year and 5-year survival rate and has little increase in toxicity-side effect.