Abstract: Objective :To determine whether the size of axillary lymph nodes on CT and palpation are predictive of the axillary lymph node metastasis in patients with breast cancer. Methods :Ninety-three patients with confirmed breast cancer undergo palpation of axillary lymph node and CT of both breasts and axillary lymph node before operation. Compare with histopathologic results of lymph node, we will determine which method is better in predictive of the axillary lymph node metastasis in patients with breast cancer. Results :Based on CT criteria of lymph node≥5mm and≥10mm and palpation, coincident value for predictive of lymph node metastasis are 72.0%, 86.0%, and 65.6% respectively, sensitivity value are 71.7%, 95.0%, and 51.7% respectively, accuracy value are 72.7%, 69.7%, 90.9% respectively. Conclusion :CT criteria of lymph node≥5mm were highly accurate for identification and diagnostic assessment of axillary lymph node and useful for evaluating the axillary status in patients with breast cancerA