Abstract: Objective :To evaluate the curative effect and patient's tolerance on late coursestereotactic conformal radiotherapy with chemotherapy for partial advanced stage non-small cell lung carcinoma. Methods :Forty-eight patients were treated with the conventional fractionation radiotherapy2Gy daily, 5 times a week, Dt 40Gy in the first 4 weeks and with stereotactic conformal radiotherapy to the primary tumor in the final 2 weeks, Dt 24Gy30Gy (4Gy5Gy fraction Dose, 3 times a week), at the same time, chemotherapy (NP scheme) given 2 period, in the first and the fifth weeks, NVB 25mg/m² intravenous injection at the first and the eighth days, DDP 30mg from the first to the third days intravenous drip. Results :All patients can fulfil the treatment plan. CR was 16.7% and PR was 75.0%. The overall response (CR+PR) was 91.7%.One -year, two year and three-year local control rates were 87.5%,50.0% and 35.7% respectively. The 1 -year, 2 -year and 3 -year survival rate were 87.5%,46.7% and 28.6%,respectively. The acute hematological toxicities (such as leukopenia) and gastroin testinal toxicities were more severe, but well tolerated after symptomatic treatment. Conclusions :There is a tendency to increase the overall survival rate on late course stereotactic conformal radiotherapy with chemotherapy for partial advanced stage non-small cell lung carcinoma.