Abstract: Objective: To study the relationship between the full- field digital mammographic features and clinicopathologic characteristics in breast cancer. Methods: Digital mammograms of178 patients with pathologically proved breast cancer were reviewed. Also, clinical and pathologic records (his-tological types and axillary nodes status) were retrospectively drawn. Results: Most of the patients with solitary micro- calcifications were young women under 50 yrs old (84.4%) and majority of the patients with micro- calcifications with the mass were the aged women. Micro- calcifications in mammography occurred frequently in intra- ductal carcinoma in situ and early invasive carcinoma. The breast cancer with expression of microcalcification cimbined with burr- like mass had a high metastasis rate of axillary lymph nodes; A high metastasis rate of axillary lymph nodes can also be found in the patients with solitary worm- like microcalcification, solitary burr- like tumor and simple non- wormlike microcalcification. Simple wormlike microcalcification accompanied with metastasis of four to nine axillary lymph nodes occurred in 75.0% (6/8) cases. The patients with microcalcification combining burr- like tumor and with metastasis of four to nine axillary lymph nodes acounted for 27.8% (10/36)of the cases, and those with metastasis of ten and over accounted for 16.7% (6/36). Conclusion: Solitary microcalcifica-tion occur frequently in young women and is usually associated with the early breast cancer. There is a close relationship between wormlike microcalcification, burr- like tumor and positive metastasis of axillary lymph nodes, which is an index of poor prognosis.