Abstract:
Objective: To assess the prognosis of hepatic resection on gastric cancer with liver metastases. Methods: Twenty- five patients were included in the retrospective study, the clinicopatho-logic features and surgical outcome were examined as prognostic factors by univariate and multivariate analysis. Results: Twenty patients underwent synchronous hepatic resection and five metachronous hepatic resection. The 1-year, 3-year and 5-year survival rates after hepatic resection was 84%, 28% and 21%, respectively. The number and the distribution of liver metastases, the type of liver surgery, the histotype of primary cancer, the lymph node involved and vascular invasion were significant prognostic factors regarding overall survival. Multivariate analysis indicated that the lymph node involved, vascular invasion of cancer cells of the primary tumor and the multiple liver metastases were independent poor prognostic factors after hepatic resection.Conclusion: Hepatic resection on liver metastases should be attempted in patients with solitary liver metastases and without lymph node metastases, as well as with vascular invasion of primary gastric cancer, in order to obtain a better prognosis.