王翠兰, 邓小梅, 孙颖, 迟兆福, 刘梅仕. 以听力障碍为首发症状的脑膜癌病的临床与影像学表现[J]. 中国肿瘤临床, 2005, 32(20): 1173-1176.
引用本文: 王翠兰, 邓小梅, 孙颖, 迟兆福, 刘梅仕. 以听力障碍为首发症状的脑膜癌病的临床与影像学表现[J]. 中国肿瘤临床, 2005, 32(20): 1173-1176.
Wang Cuilan, Deng Xiaomei, Sun Ying, Chi Zhaofu, Liu Meishi. Clinical Manifestation and Imaging Findings of Meningeal Carcinomatosis with an Initial Presentation of Sudden Onset Dysaudia[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2005, 32(20): 1173-1176.
Citation: Wang Cuilan, Deng Xiaomei, Sun Ying, Chi Zhaofu, Liu Meishi. Clinical Manifestation and Imaging Findings of Meningeal Carcinomatosis with an Initial Presentation of Sudden Onset Dysaudia[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2005, 32(20): 1173-1176.

以听力障碍为首发症状的脑膜癌病的临床与影像学表现

Clinical Manifestation and Imaging Findings of Meningeal Carcinomatosis with an Initial Presentation of Sudden Onset Dysaudia

  • 摘要: 目的: 探讨以听力障碍为首发症状的脑膜癌病的临床与影像学表现。 方法: 分析7例患者的临床资料、脑脊液和颅脑MRI检查结果。 结果: 7例患者,临床表现多样,伴有脑神经损害(Ⅶ神经3例,Ⅵ神经2例,Ⅸ、Ⅹ神经1例,Ⅴ神经1例)和脊神经损害(肢体周围性瘫痪2例),均有脑膜刺激征。 结论: 以听力障碍为首发症状的脑膜癌病易误诊,脑脊液发现癌细胞仍是确诊脑膜癌病最简便与最直接的证据,软脑膜-蛛网膜下腔强化是脑膜癌病患者较具特征性的影像学表现。

     

    Abstract: Objective : To investigate the clinical manifestation and imaging findings of meningeal carcinomatosis (MC) with an initial presentation of sudden onset dysaudia. Methods :The clinical data, cerebrospinal fluid examination and the results of cranial MRI in 7 patients with MC wire reviewed. Results :Seven Patients with MC may present with a variety of symptoms and signs as the cranial nerves palsies (VII nerve 3 cases,VI nerve 2 cases,IX、X nerve 1 case, V nerve 1 case )and the spinal roots palsies(peripheral paralysis of extremities 2 cases), all had meningeal irritation. Conclusions :MC with an initial presentation of sudden onset dysaudia is easy to cause an misdiagnosis. Cytologic study of CSF is still the most convenient and direct evidence in diagnosis of MC. Abnormal pia- subarachnoid space enheacement is the characteristic imaging manifestation for the diagnosis of MC.

     

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