Abstract: Gemcitabine (iv over 30 minutes) is the standard therapy for inoperable pancreatic cancer of advanced stage. In order to improve the effect of gemcitabine and the prognosis of pancreatic cancer, lots of clinical trials are being conducted, i.e. to change the method of administration, combinewith other drugs, or to be replaced by other more efficient drugs. The article summarizes the ongoing clinical trials in American at present, that can be searched at data base of the clinical trials on Internet(www.clinicaltrials.gov).