Abstract: Objective : To evaluate the performance of the three kinds of the risk of malignancy in-dices(RMI) in discriminating benign from malignant adnexal masses. Methods : The three kinds of models(The RMI is the perduct of menopausal score, ultrasound scores, and the absolute value of serum CA125 levels) were perspectively applied to predict the likelihood of malignancy in 180 patients with adnexal masses, their diagnostic values were analysed in the different histological types and FIGO stages of tumours, their diagnostic capability were compared with single indices, their best suitable cut of value was compared with result that original research reported. Results : The diagnostic rates of three kinds of models in epithelial malignant tumours (RMI1: 82.6W, RMI2: 91.3%, RMI3: 86.9%) were significantly higher than in the other histological types (50.0%) (8<0.001); In the group of patients with borderline tumour and stages I Ⅰ、Ⅱ of ovarian cancer, their diagnostic capabilities were significantly lower than in the group of patients with stages Ⅲ、Ⅳ of ovarian cancer (P<0.05); Their total diagnostic capabilities exceeded that of CA125 level and ultrasound scores (P>0.05 )； There were no differences among the diagnostic capabilities of three kinds of models (P=0.05), their best suitable cut of values were level of 100 other than level of 200 that was originally reported. Conclusion : The three kinds of RMI hold some values in discriminating benign from malignant adnexal masses, worthwhile they need to be improved.