Abstract: Objective: To study the related questions of early diagnosis and treatment for postoperative recurrence of advanced gastric cancer. Methods: The clinical data and survival rate of 106 cases with postoperative recurrence of advanced gastric cancer, from Dec 1997 to Dec 2004, were retrospectively analyzed. Kaplan-Meier was used to depict the survival curves and to compare the differences among the cumulative survival rates according to varied treatments. Results: The mean recurrence time was 18.3 months. 81.1% of postoperative recurrence was found within 2 years. Radicalresection, palliative resection and bypass process were carried out in 17 patients, 19 patients and 21patients, for which the median survival time was ≧ 24.0, 9.0, and 3.0 months, respectively. The difference among them was significant (P<0.05). The median survival time was 2 months for the 49patients with supportive treatment, and it was remarkably lower than those of the surgical operation groups (P<0.05). Conclusions: The prognosis of recurrent gastric cancer is poor. Early diagnosis and active treatment can prolong survival time of the patients.